2s.io

https://2s.io/api/medical/drug-price

Shares a payout wallet with 441 other endpoints — its adoption is attributed from that shared wallet's traffic, not earned exclusively.

Look up US drug pricing from CMS NADAC (National Average Drug Acquisition Cost) — the benchmark per-unit acquisition cost CMS surveys from retail pharmacies and publishes weekly. Pass ndc (11-digit National Drug Code) for an exact product, or name (drug name/description keyword, e.g. 'atorvastatin 10 mg') to search. Returns rows with the NDC, description, nadacPerUnit (USD per pricing unit), pricingUnit (EA/ML/GM), effectiveDate, OTC flag, and brand/generic classification — most recent effective date first. Real surveyed acquisition costs instead of model-guessed prices. Public domain; the current-year dataset is resolved automatically. NADAC is an acquisition-cost benchmark, not a retail or insured price.

63
reliability

Reliability & health

Uptime and response time from our own unpaid probes, plus the reliability score built from them.

7 days 30 days

Uptime

100.0% avg
0% 50% 100% Sat 1 AMMon 9 AMWed 4 PMSat 12 AM

Response time

p50 58ms · p95 127ms
0ms 150ms 300ms Sat 1 AMMon 9 AMWed 4 PMSat 12 AM
Data table
Reliability history per time bucket over the last 7 days (hourly).
Bucket Uptime Probes Response time
8/15/2026, 1:00:00 AM 100% 1 49ms
8/15/2026, 3:00:00 AM 100% 1 68ms
8/15/2026, 4:00:00 AM 100% 1 64ms
8/15/2026, 5:00:00 AM 100% 1 53ms
8/15/2026, 6:00:00 AM 100% 1 58ms
8/15/2026, 7:00:00 AM 100% 1 55ms
8/15/2026, 8:00:00 AM 100% 1 67ms
8/15/2026, 9:00:00 AM 100% 1 52ms
8/15/2026, 10:00:00 AM 100% 1 58ms
8/15/2026, 12:00:00 PM 100% 1 60ms
8/15/2026, 1:00:00 PM 100% 1 55ms
8/15/2026, 2:00:00 PM 100% 1 61ms
8/15/2026, 3:00:00 PM 100% 1 71ms
8/15/2026, 4:00:00 PM 100% 1 52ms
8/15/2026, 5:00:00 PM 100% 1 51ms
8/15/2026, 7:00:00 PM 100% 1 49ms
8/15/2026, 8:00:00 PM 100% 1 51ms
8/15/2026, 9:00:00 PM 100% 1 67ms
8/15/2026, 10:00:00 PM 100% 1 66ms
8/15/2026, 11:00:00 PM 100% 1 80ms
8/16/2026, 12:00:00 AM 100% 1 66ms
8/16/2026, 2:00:00 AM 100% 1 61ms
8/16/2026, 3:00:00 AM 100% 1 104ms
8/16/2026, 4:00:00 AM 100% 1 52ms
8/16/2026, 5:00:00 AM 100% 1 54ms
8/16/2026, 6:00:00 AM 100% 1 55ms
8/16/2026, 7:00:00 AM 100% 1 63ms
8/16/2026, 9:00:00 AM 100% 1 63ms
8/16/2026, 10:00:00 AM 100% 1 49ms
8/16/2026, 11:00:00 AM 100% 1 50ms
8/16/2026, 12:00:00 PM 100% 1 56ms
8/16/2026, 1:00:00 PM 100% 1 55ms
8/16/2026, 2:00:00 PM 100% 1 54ms
8/16/2026, 4:00:00 PM 100% 1 53ms
8/16/2026, 5:00:00 PM 100% 1 49ms
8/16/2026, 6:00:00 PM 100% 1 44ms
8/16/2026, 7:00:00 PM 100% 1 61ms
8/16/2026, 8:00:00 PM 100% 1 42ms
8/16/2026, 9:00:00 PM 100% 1 52ms
8/16/2026, 11:00:00 PM 100% 1 66ms
8/17/2026, 12:00:00 AM 100% 1 82ms
8/17/2026, 1:00:00 AM 100% 1 54ms
8/17/2026, 2:00:00 AM 100% 1 48ms
8/17/2026, 3:00:00 AM 100% 1 54ms
8/17/2026, 4:00:00 AM 100% 1 47ms
8/17/2026, 6:00:00 AM 100% 1 58ms
8/17/2026, 7:00:00 AM 100% 1 160ms
8/17/2026, 8:00:00 AM 100% 1 57ms
8/17/2026, 9:00:00 AM 100% 1 57ms
8/17/2026, 10:00:00 AM 100% 1 68ms
8/17/2026, 11:00:00 AM 100% 1 82ms
8/17/2026, 1:00:00 PM 100% 1 54ms
8/17/2026, 2:00:00 PM 100% 1 74ms
8/17/2026, 3:00:00 PM 100% 1 53ms
8/17/2026, 4:00:00 PM 100% 1 55ms
8/17/2026, 5:00:00 PM 100% 1 93ms
8/17/2026, 6:00:00 PM 100% 1 68ms
8/17/2026, 8:00:00 PM 100% 1 58ms
8/17/2026, 9:00:00 PM 100% 1 64ms
8/17/2026, 10:00:00 PM 100% 1 53ms
8/17/2026, 11:00:00 PM 100% 1 98ms
8/18/2026, 12:00:00 AM 100% 1 91ms
8/18/2026, 1:00:00 AM 100% 1 67ms
8/18/2026, 3:00:00 AM 100% 1 48ms
8/18/2026, 4:00:00 AM 100% 1 51ms
8/18/2026, 5:00:00 AM 100% 1 53ms
8/18/2026, 6:00:00 AM 100% 1 137ms
8/18/2026, 7:00:00 AM 100% 1 71ms
8/18/2026, 8:00:00 AM 100% 1 67ms
8/18/2026, 10:00:00 AM 100% 1 73ms
8/18/2026, 11:00:00 AM 100% 1 149ms
8/18/2026, 12:00:00 PM 100% 1 162ms
8/18/2026, 1:00:00 PM 100% 1 104ms
8/18/2026, 2:00:00 PM 100% 1 58ms
8/18/2026, 3:00:00 PM 100% 1 47ms
8/18/2026, 5:00:00 PM 100% 1 51ms
8/18/2026, 6:00:00 PM 100% 1 51ms
8/18/2026, 7:00:00 PM 100% 1 66ms
8/18/2026, 8:00:00 PM 100% 1 92ms
8/18/2026, 9:00:00 PM 100% 1 57ms
8/18/2026, 10:00:00 PM 100% 1 47ms
8/19/2026, 12:00:00 AM 100% 1 59ms
8/19/2026, 1:00:00 AM 100% 1 80ms
8/19/2026, 2:00:00 AM 100% 1 51ms
8/19/2026, 3:00:00 AM 100% 1 54ms
8/19/2026, 4:00:00 AM 100% 1 49ms
8/19/2026, 5:00:00 AM 100% 1 43ms
8/19/2026, 7:00:00 AM 100% 1 49ms
8/19/2026, 8:00:00 AM 100% 1 68ms
8/19/2026, 9:00:00 AM 100% 1 58ms
8/19/2026, 10:00:00 AM 100% 1 63ms
8/19/2026, 11:00:00 AM 100% 1 56ms
8/19/2026, 12:00:00 PM 100% 1 50ms
8/19/2026, 2:00:00 PM 100% 1 47ms
8/19/2026, 3:00:00 PM 100% 1 67ms
8/19/2026, 4:00:00 PM 100% 1 64ms
8/19/2026, 5:00:00 PM 100% 1 59ms
8/19/2026, 6:00:00 PM 100% 1 64ms
8/19/2026, 7:00:00 PM 100% 1 67ms
8/19/2026, 8:00:00 PM 100% 1 65ms
8/19/2026, 10:00:00 PM 100% 1 62ms
8/19/2026, 11:00:00 PM 100% 1 59ms
8/20/2026, 12:00:00 AM 100% 1 58ms
8/20/2026, 1:00:00 AM 100% 1 52ms
8/20/2026, 2:00:00 AM 100% 1 49ms
8/20/2026, 3:00:00 AM 100% 1 68ms
8/20/2026, 5:00:00 AM 100% 1 68ms
8/20/2026, 6:00:00 AM 100% 1 59ms
8/20/2026, 7:00:00 AM 100% 1 61ms
8/20/2026, 8:00:00 AM 100% 1 74ms
8/20/2026, 9:00:00 AM 100% 1 66ms
8/20/2026, 10:00:00 AM 100% 1 55ms
8/20/2026, 12:00:00 PM 100% 1 60ms
8/20/2026, 1:00:00 PM 100% 1 62ms
8/20/2026, 2:00:00 PM 100% 1 67ms
8/20/2026, 3:00:00 PM 100% 1 60ms
8/20/2026, 4:00:00 PM 100% 1 68ms
8/20/2026, 6:00:00 PM 100% 1 58ms
8/20/2026, 7:00:00 PM 100% 1 50ms
8/20/2026, 8:00:00 PM 100% 1 55ms
8/20/2026, 9:00:00 PM 100% 1 52ms
8/20/2026, 11:00:00 PM 100% 1 51ms
8/21/2026, 12:00:00 AM 100% 1 54ms
8/21/2026, 1:00:00 AM 100% 1 55ms
8/21/2026, 2:00:00 AM 100% 1 55ms
8/21/2026, 3:00:00 AM 100% 1 231ms
8/21/2026, 4:00:00 AM 100% 1 60ms
8/21/2026, 5:00:00 AM 100% 1 256ms
8/21/2026, 6:00:00 AM 100% 1 51ms
8/21/2026, 8:00:00 AM 100% 1 47ms
8/21/2026, 9:00:00 AM 100% 1 56ms
8/21/2026, 10:00:00 AM 100% 1 62ms
8/21/2026, 11:00:00 AM 100% 1 51ms
8/21/2026, 12:00:00 PM 100% 2 48ms
8/21/2026, 1:00:00 PM 100% 1 59ms
8/21/2026, 3:00:00 PM 100% 1 54ms
8/21/2026, 4:00:00 PM 100% 1 67ms
8/21/2026, 5:00:00 PM 100% 1 64ms
8/21/2026, 6:00:00 PM 100% 1 61ms
8/21/2026, 7:00:00 PM 100% 1 58ms
8/21/2026, 8:00:00 PM 100% 1 61ms
8/21/2026, 9:00:00 PM 100% 1 56ms
8/21/2026, 10:00:00 PM 100% 1 77ms
8/22/2026, 12:00:00 AM 100% 1 245ms
63
Composite reliability — the weighted average of the dimensions below, on a 0–100 scale.
Availability
100

How often it was reachable when we probed it (weight 35%).

Latency
100

How quickly it answers when it is up — fast scores high (weight 20%).

Security
100

Whether it serves over working TLS / https (weight 15%).

Transparency
61

Whether the operator disclosed what it does — description, schema, identity (weight 15%).

Activity
2

Observed on-chain payments to this endpoint's wallet — transactions, volume, and distinct paying wallets over the last month (weight 15%; not yet measured when we have not seen its wallet settle).

Confidence 100% — how much probe evidence backs this score. A thin history is flagged, not hidden.

See the scoring methodology for exactly how each number is computed.

Payment

Currencies
USDC
Networks
base, solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp
Facilitator
unknown
SDK
unknown

Operator

Company
inferred — unknown
Jurisdiction
—
Registrar
—
Domain registered
—
Hosting network
VERCEL-09
Hosting country
—

Operator context is derived from public RDAP/TLS records and unverified. Company and country are only available for endpoints that publish them (an OV/EV TLS certificate or a non-redacted domain record); most endpoints are CDN-fronted and disclose neither.

On-chain activity (base)

12,279
payments (30d)
35.43
USD volume (30d)
181
paying wallets (30d)

Payments per day

last payment 8/21/2026
0 1000 2000 Jul 24Aug 2Aug 12Aug 21
Data table
Settled payments per day.
Day Payments Volume (USD) Paying wallets
7/24/2026 1,232 2.49 117
7/25/2026 1,341 2.61 128
7/26/2026 915 1.98 107
7/27/2026 1,175 2.1 107
7/28/2026 762 1.71 86
7/29/2026 852 1.67 97
7/30/2026 818 1.74 97
7/31/2026 882 1.7 94
8/1/2026 633 1.24 82
8/2/2026 604 1.12 76
8/3/2026 358 1.6 47
8/4/2026 530 3.35 70
8/5/2026 408 2.76 42
8/6/2026 272 2.14 32
8/7/2026 164 1.37 23
8/8/2026 127 1.51 17
8/9/2026 60 0.33 10
8/10/2026 109 0.36 8
8/11/2026 84 0.25 8
8/12/2026 84 0.25 6
8/13/2026 73 0.21 6
8/14/2026 167 1.05 6
8/15/2026 24 0.1 4
8/16/2026 338 0.86 2
8/17/2026 63 0.18 3
8/18/2026 55 0.16 2
8/19/2026 84 0.23 3
8/20/2026 43 0.25 6
8/21/2026 22 0.1 5

This payout wallet is shared: figures cover all 442 endpoints paid at it, since payments cannot be attributed to one of them. Only payments settled on chains and facilitators we index.

Linked by wallet — likely same operator

On-chain agent identity and the x402 endpoint that shares its settlement wallet.

https://2s.io/api/crypto/ens-resolve x402 endpoint https://2s-3cpr6qm6j-alleyford.vercel.app/api/convert/unit x402 endpoint
Response schema 
{
  "properties": {
    "data": {
      "additionalProperties": false,
      "properties": {
        "items": {
          "items": {
            "additionalProperties": false,
            "properties": {
              "asOfDate": {
                "nullable": true,
                "type": "string"
              },
              "classification": {
                "description": "G = generic, B = brand",
                "nullable": true,
                "type": "string"
              },
              "description": {
                "type": "string"
              },
              "effectiveDate": {
                "nullable": true,
                "type": "string"
              },
              "nadacPerUnit": {
                "nullable": true,
                "type": "number"
              },
              "ndc": {
                "type": "string"
              },
              "otc": {
                "nullable": true,
                "type": "boolean"
              },
              "pricingUnit": {
                "nullable": true,
                "type": "string"
              }
            },
            "required": [
              "ndc",
              "description",
              "nadacPerUnit",
              "pricingUnit",
              "effectiveDate",
              "otc",
              "classification",
              "asOfDate"
            ],
            "type": "object"
          },
          "type": "array"
        },
        "meta": {
          "additionalProperties": false,
          "properties": {
            "datasetYear": {
              "type": "string"
            },
            "query": {
              "additionalProperties": false,
              "properties": {
                "name": {
                  "nullable": true,
                  "type": "string"
                },
                "ndc": {
                  "nullable": true,
                  "type": "string"
                }
              },
              "required": [
                "ndc",
                "name"
              ],
              "type": "object"
            },
            "total": {
              "type": "integer"
            }
          },
          "required": [
            "query",
            "datasetYear",
            "total"
          ],
          "type": "object"
        },
        "ok": {
          "enum": [
            true
          ],
          "type": "boolean"
        },
        "source": {
          "$ref": "#/components/schemas/Source"
        },
        "total": {
          "description": "Total matching rows upstream; null when unknown.",
          "nullable": true,
          "type": "integer"
        }
      },
      "required": [
        "ok",
        "items",
        "total",
        "source"
      ],
      "type": "object"
    },
    "meta": {
      "$ref": "#/components/schemas/CallMeta"
    }
  },
  "required": [
    "data",
    "meta"
  ],
  "type": "object"
}