2s.io

https://2s.io/api/medical/drug-label

Shares a payout wallet with 441 other endpoints — its adoption is attributed from that shared wallet's traffic, not earned exclusively.

Authoritative FDA drug label (Structured Product Labeling). Give a drug name (brand, generic, or substance), or an exact NDC, RxCUI, or SPL set_id, and get back the FDA-approved label split into the sections agents need: boxed warning, indications and usage, dosage and administration, contraindications, warnings, adverse reactions, drug interactions, use in specific populations, pregnancy, mechanism of action, and active/inactive ingredients. Each record also carries identity metadata (brand/generic names, manufacturer, NDCs, RxCUIs, route, DEA schedule, OTC vs prescription) plus a hasBoxedWarning flag. Free, public-domain US government data. Point-in-time public records, not medical advice. Use for prescribing-support, pharmacy, and clinical agents that must read the real label rather than guess it.

64
reliability

Reliability & health

Uptime and response time from our own unpaid probes, plus the reliability score built from them.

7 days 30 days

Uptime

100.0% avg
0% 50% 100% Fri 2 AMSun 8 AMTue 4 PMFri 12 AM

Response time

p50 59ms · p95 173ms
0ms 200ms 400ms Fri 2 AMSun 8 AMTue 4 PMFri 12 AM
Data table
Reliability history per time bucket over the last 7 days (hourly).
Bucket Uptime Probes Response time
8/14/2026, 2:00:00 AM 100% 1 48ms
8/14/2026, 3:00:00 AM 100% 1 52ms
8/14/2026, 4:00:00 AM 100% 1 48ms
8/14/2026, 5:00:00 AM 100% 1 87ms
8/14/2026, 6:00:00 AM 100% 1 61ms
8/14/2026, 8:00:00 AM 100% 1 54ms
8/14/2026, 9:00:00 AM 100% 1 63ms
8/14/2026, 10:00:00 AM 100% 1 57ms
8/14/2026, 11:00:00 AM 100% 1 64ms
8/14/2026, 12:00:00 PM 100% 1 58ms
8/14/2026, 2:00:00 PM 100% 1 54ms
8/14/2026, 3:00:00 PM 100% 1 74ms
8/14/2026, 4:00:00 PM 100% 1 41ms
8/14/2026, 5:00:00 PM 100% 1 45ms
8/14/2026, 6:00:00 PM 100% 1 50ms
8/14/2026, 8:00:00 PM 100% 1 58ms
8/14/2026, 9:00:00 PM 100% 1 174ms
8/14/2026, 10:00:00 PM 100% 1 269ms
8/14/2026, 11:00:00 PM 100% 1 130ms
8/15/2026, 12:00:00 AM 100% 1 127ms
8/15/2026, 1:00:00 AM 100% 1 54ms
8/15/2026, 2:00:00 AM 100% 1 55ms
8/15/2026, 3:00:00 AM 100% 1 79ms
8/15/2026, 5:00:00 AM 100% 1 60ms
8/15/2026, 6:00:00 AM 100% 1 53ms
8/15/2026, 7:00:00 AM 100% 1 71ms
8/15/2026, 8:00:00 AM 100% 1 71ms
8/15/2026, 9:00:00 AM 100% 1 57ms
8/15/2026, 10:00:00 AM 100% 1 46ms
8/15/2026, 11:00:00 AM 100% 1 49ms
8/15/2026, 1:00:00 PM 100% 1 45ms
8/15/2026, 2:00:00 PM 100% 1 65ms
8/15/2026, 3:00:00 PM 100% 1 142ms
8/15/2026, 4:00:00 PM 100% 1 49ms
8/15/2026, 5:00:00 PM 100% 1 73ms
8/15/2026, 6:00:00 PM 100% 1 103ms
8/15/2026, 8:00:00 PM 100% 1 74ms
8/15/2026, 9:00:00 PM 100% 1 57ms
8/15/2026, 10:00:00 PM 100% 1 65ms
8/15/2026, 11:00:00 PM 100% 1 59ms
8/16/2026, 12:00:00 AM 100% 1 58ms
8/16/2026, 1:00:00 AM 100% 1 55ms
8/16/2026, 3:00:00 AM 100% 1 82ms
8/16/2026, 4:00:00 AM 100% 1 59ms
8/16/2026, 5:00:00 AM 100% 1 51ms
8/16/2026, 6:00:00 AM 100% 1 160ms
8/16/2026, 7:00:00 AM 100% 1 53ms
8/16/2026, 8:00:00 AM 100% 1 54ms
8/16/2026, 10:00:00 AM 100% 1 68ms
8/16/2026, 11:00:00 AM 100% 1 64ms
8/16/2026, 12:00:00 PM 100% 1 64ms
8/16/2026, 1:00:00 PM 100% 1 59ms
8/16/2026, 2:00:00 PM 100% 1 54ms
8/16/2026, 3:00:00 PM 100% 1 54ms
8/16/2026, 5:00:00 PM 100% 1 58ms
8/16/2026, 6:00:00 PM 100% 1 62ms
8/16/2026, 7:00:00 PM 100% 1 51ms
8/16/2026, 8:00:00 PM 100% 1 133ms
8/16/2026, 9:00:00 PM 100% 1 58ms
8/16/2026, 10:00:00 PM 100% 1 57ms
8/17/2026, 12:00:00 AM 100% 1 52ms
8/17/2026, 1:00:00 AM 100% 1 132ms
8/17/2026, 2:00:00 AM 100% 1 58ms
8/17/2026, 3:00:00 AM 100% 1 70ms
8/17/2026, 4:00:00 AM 100% 1 65ms
8/17/2026, 5:00:00 AM 100% 1 53ms
8/17/2026, 7:00:00 AM 100% 1 81ms
8/17/2026, 8:00:00 AM 100% 1 53ms
8/17/2026, 9:00:00 AM 100% 1 60ms
8/17/2026, 10:00:00 AM 100% 1 111ms
8/17/2026, 11:00:00 AM 100% 1 63ms
8/17/2026, 12:00:00 PM 100% 1 59ms
8/17/2026, 2:00:00 PM 100% 1 64ms
8/17/2026, 3:00:00 PM 100% 1 53ms
8/17/2026, 4:00:00 PM 100% 1 60ms
8/17/2026, 5:00:00 PM 100% 1 46ms
8/17/2026, 6:00:00 PM 100% 1 59ms
8/17/2026, 7:00:00 PM 100% 1 56ms
8/17/2026, 9:00:00 PM 100% 1 69ms
8/17/2026, 10:00:00 PM 100% 1 54ms
8/17/2026, 11:00:00 PM 100% 1 75ms
8/18/2026, 12:00:00 AM 100% 1 50ms
8/18/2026, 1:00:00 AM 100% 1 54ms
8/18/2026, 2:00:00 AM 100% 1 61ms
8/18/2026, 4:00:00 AM 100% 1 85ms
8/18/2026, 5:00:00 AM 100% 1 127ms
8/18/2026, 6:00:00 AM 100% 1 59ms
8/18/2026, 7:00:00 AM 100% 1 54ms
8/18/2026, 8:00:00 AM 100% 1 63ms
8/18/2026, 9:00:00 AM 100% 1 61ms
8/18/2026, 11:00:00 AM 100% 1 56ms
8/18/2026, 12:00:00 PM 100% 1 320ms
8/18/2026, 1:00:00 PM 100% 1 148ms
8/18/2026, 2:00:00 PM 100% 1 58ms
8/18/2026, 3:00:00 PM 100% 1 58ms
8/18/2026, 4:00:00 PM 100% 1 62ms
8/18/2026, 6:00:00 PM 100% 1 52ms
8/18/2026, 7:00:00 PM 100% 1 58ms
8/18/2026, 8:00:00 PM 100% 1 53ms
8/18/2026, 9:00:00 PM 100% 1 52ms
8/18/2026, 10:00:00 PM 100% 1 60ms
8/18/2026, 11:00:00 PM 100% 1 51ms
8/19/2026, 1:00:00 AM 100% 1 50ms
8/19/2026, 2:00:00 AM 100% 1 221ms
8/19/2026, 3:00:00 AM 100% 1 55ms
8/19/2026, 4:00:00 AM 100% 1 50ms
8/19/2026, 5:00:00 AM 100% 1 60ms
8/19/2026, 6:00:00 AM 100% 1 394ms
8/19/2026, 8:00:00 AM 100% 1 81ms
8/19/2026, 9:00:00 AM 100% 1 46ms
8/19/2026, 10:00:00 AM 100% 1 61ms
8/19/2026, 11:00:00 AM 100% 1 99ms
8/19/2026, 12:00:00 PM 100% 1 53ms
8/19/2026, 1:00:00 PM 100% 1 50ms
8/19/2026, 3:00:00 PM 100% 1 73ms
8/19/2026, 4:00:00 PM 100% 1 48ms
8/19/2026, 5:00:00 PM 100% 1 65ms
8/19/2026, 6:00:00 PM 100% 1 60ms
8/19/2026, 7:00:00 PM 100% 1 52ms
8/19/2026, 8:00:00 PM 100% 1 64ms
8/19/2026, 9:00:00 PM 100% 1 54ms
8/19/2026, 11:00:00 PM 100% 1 58ms
8/20/2026, 12:00:00 AM 100% 1 48ms
8/20/2026, 1:00:00 AM 100% 1 71ms
8/20/2026, 2:00:00 AM 100% 1 54ms
8/20/2026, 3:00:00 AM 100% 1 59ms
8/20/2026, 4:00:00 AM 100% 1 122ms
8/20/2026, 6:00:00 AM 100% 1 109ms
8/20/2026, 7:00:00 AM 100% 1 53ms
8/20/2026, 8:00:00 AM 100% 1 64ms
8/20/2026, 9:00:00 AM 100% 1 59ms
8/20/2026, 10:00:00 AM 100% 1 51ms
8/20/2026, 11:00:00 AM 100% 1 58ms
8/20/2026, 1:00:00 PM 100% 1 48ms
8/20/2026, 2:00:00 PM 100% 1 64ms
8/20/2026, 3:00:00 PM 100% 1 51ms
8/20/2026, 4:00:00 PM 100% 1 56ms
8/20/2026, 6:00:00 PM 100% 1 54ms
8/20/2026, 7:00:00 PM 100% 1 65ms
8/20/2026, 8:00:00 PM 100% 1 241ms
8/20/2026, 9:00:00 PM 100% 1 256ms
8/20/2026, 10:00:00 PM 100% 1 271ms
8/21/2026, 12:00:00 AM 100% 1 165ms
64
Composite reliability — the weighted average of the dimensions below, on a 0–100 scale.
Availability
100

How often it was reachable when we probed it (weight 35%).

Latency
100

How quickly it answers when it is up — fast scores high (weight 20%).

Security
100

Whether it serves over working TLS / https (weight 15%).

Transparency
61

Whether the operator disclosed what it does — description, schema, identity (weight 15%).

Activity
4

Observed on-chain payments to this endpoint's wallet — transactions, volume, and distinct paying wallets over the last month (weight 15%; not yet measured when we have not seen its wallet settle).

Confidence 100% — how much probe evidence backs this score. A thin history is flagged, not hidden.

See the scoring methodology for exactly how each number is computed.

Payment

Currencies
USDC
Networks
base, solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp
Facilitator
unknown
SDK
unknown

Operator

Company
inferred — unknown
Jurisdiction
—
Registrar
—
Domain registered
—
Hosting network
VERCEL-09
Hosting country
—

Operator context is derived from public RDAP/TLS records and unverified. Company and country are only available for endpoints that publish them (an OV/EV TLS certificate or a non-redacted domain record); most endpoints are CDN-fronted and disclose neither.

On-chain activity (base)

12,886
payments (30d)
36.99
USD volume (30d)
181
paying wallets (30d)

Payments per day

last payment 8/20/2026
0 1000 2000 Jul 23Aug 1Aug 11Aug 20
Data table
Settled payments per day.
Day Payments Volume (USD) Paying wallets
7/23/2026 629 1.66 89
7/24/2026 1,232 2.49 117
7/25/2026 1,341 2.61 128
7/26/2026 915 1.98 107
7/27/2026 1,175 2.1 107
7/28/2026 762 1.71 86
7/29/2026 852 1.67 97
7/30/2026 818 1.74 97
7/31/2026 882 1.7 94
8/1/2026 633 1.24 82
8/2/2026 604 1.12 76
8/3/2026 358 1.6 47
8/4/2026 530 3.35 70
8/5/2026 408 2.76 42
8/6/2026 272 2.14 32
8/7/2026 164 1.37 23
8/8/2026 127 1.51 17
8/9/2026 60 0.33 10
8/10/2026 109 0.36 8
8/11/2026 84 0.25 8
8/12/2026 84 0.25 6
8/13/2026 73 0.21 6
8/14/2026 167 1.05 6
8/15/2026 24 0.1 4
8/16/2026 338 0.86 2
8/17/2026 63 0.18 3
8/18/2026 55 0.16 2
8/19/2026 84 0.23 3
8/20/2026 43 0.25 6

This payout wallet is shared: figures cover all 442 endpoints paid at it, since payments cannot be attributed to one of them. Only payments settled on chains and facilitators we index.

Linked by wallet — likely same operator

On-chain agent identity and the x402 endpoint that shares its settlement wallet.

https://2s.io/api/crypto/ens-resolve x402 endpoint https://2s-3cpr6qm6j-alleyford.vercel.app/api/convert/unit x402 endpoint
Response schema 
{
  "properties": {
    "data": {
      "additionalProperties": false,
      "properties": {
        "hasBoxedWarning": {
          "type": "boolean"
        },
        "labels": {
          "items": {
            "additionalProperties": false,
            "properties": {
              "activeIngredient": {
                "nullable": true,
                "type": "string"
              },
              "adverseReactions": {
                "nullable": true,
                "type": "string"
              },
              "boxedWarning": {
                "nullable": true,
                "type": "string"
              },
              "brandNames": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              },
              "contraindications": {
                "nullable": true,
                "type": "string"
              },
              "deaSchedule": {
                "nullable": true,
                "type": "string"
              },
              "description": {
                "nullable": true,
                "type": "string"
              },
              "doNotUse": {
                "nullable": true,
                "type": "string"
              },
              "dosageAndAdministration": {
                "nullable": true,
                "type": "string"
              },
              "drugInteractions": {
                "nullable": true,
                "type": "string"
              },
              "effectiveTime": {
                "nullable": true,
                "type": "string"
              },
              "genericNames": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              },
              "inactiveIngredient": {
                "nullable": true,
                "type": "string"
              },
              "indicationsAndUsage": {
                "nullable": true,
                "type": "string"
              },
              "isOtc": {
                "nullable": true,
                "type": "boolean"
              },
              "manufacturerNames": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              },
              "mechanismOfAction": {
                "nullable": true,
                "type": "string"
              },
              "pregnancy": {
                "nullable": true,
                "type": "string"
              },
              "productNdc": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              },
              "productType": {
                "nullable": true,
                "type": "string"
              },
              "purpose": {
                "nullable": true,
                "type": "string"
              },
              "routes": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              },
              "rxcui": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              },
              "setId": {
                "nullable": true,
                "type": "string"
              },
              "splId": {
                "nullable": true,
                "type": "string"
              },
              "stopUse": {
                "nullable": true,
                "type": "string"
              },
              "substanceNames": {
                "items": {
                  "type": "string"
                },
                "type": "array"
              },
              "useInSpecificPopulations": {
                "nullable": true,
                "type": "string"
              },
              "warnings": {
                "nullable": true,
                "type": "string"
              },
              "whenUsing": {
                "nullable": true,
                "type": "string"
              }
            },
            "required": [
              "setId",
              "splId",
              "effectiveTime",
              "brandNames",
              "genericNames",
              "substanceNames",
              "manufacturerNames",
              "productNdc",
              "routes",
              "productType",
              "rxcui",
              "deaSchedule",
              "isOtc",
              "boxedWarning",
              "indicationsAndUsage",
              "dosageAndAdministration",
              "contraindications",
              "warnings",
              "adverseReactions",
              "drugInteractions",
              "useInSpecificPopulations",
              "pregnancy",
              "mechanismOfAction",
              "activeIngredient",
              "inactiveIngredient",
              "purpose",
              "doNotUse",
              "whenUsing",
              "stopUse",
              "description"
            ],
            "type": "object"
          },
          "type": "array"
        },
        "query": {
          "additionalProperties": false,
          "properties": {
            "drug": {
              "nullable": true,
              "type": "string"
            },
            "limit": {
              "type": "number"
            },
            "ndc": {
              "nullable": true,
              "type": "string"
            },
            "rxcui": {
              "nullable": true,
              "type": "string"
            },
            "setId": {
              "nullable": true,
              "type": "string"
            }
          },
          "required": [
            "drug",
            "ndc",
            "rxcui",
            "setId",
            "limit"
          ],
          "type": "object"
        },
        "returned": {
          "type": "number"
        },
        "source": {
          "$ref": "#/components/schemas/Source"
        },
        "totalCount": {
          "type": "number"
        }
      },
      "required": [
        "query",
        "totalCount",
        "returned",
        "hasBoxedWarning",
        "labels",
        "source"
      ],
      "type": "object"
    },
    "meta": {
      "$ref": "#/components/schemas/CallMeta"
    }
  },
  "required": [
    "data",
    "meta"
  ],
  "type": "object"
}