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1,489–1,512 of 21,5782s.io
2s.io
Look up a protein in UniProtKB by accession (e.g. "P04637", "Q9Y6K9", "P0DTC2"). Returns the entry id, reviewed (Swiss-Prot) flag, recommended + alternative protein names, gene names, organism + taxid, sequence length and molecular weight, the curated function description, subcellular locations, Gene Ontology terms (id + term + aspect: biological_process / molecular_function / cellular_component), PDB structure ids, and keywords. Bioinformatics, structural biology, drug-target research, education. Gene-centric sibling: /api/bio/gene. CC-BY UniProt data.
2s.io
2s.io
Latest benchmark commodity price with the prior value + % change. Pass commodity for one, or omit for all. Commodities: wti, brent, natural-gas, gasoline, diesel, heating-oil, propane, copper, aluminum, corn, wheat, sugar — i.e. crude oil (WTI + Brent), natural gas, gasoline, diesel, heating oil, propane, gold, copper, aluminum, corn, wheat, sugar. Each result names the FRED series ID + unit ($/barrel, $/gallon, $/troy oz, $/metric ton...). Daily benchmarks report a daily date; global-price series are monthly. Source: EIA / LBMA / IMF via FRED (St. Louis Fed).
2s.io
2s.io
Centralized-exchange 24h ticker for a spot pair (e.g. BTC-USD), free/keyless: current price, best bid/ask, 24h open/high/low, 24h + 30d volume, and 24h percent change. Real CEX spot quote — distinct from crypto.token-price (CoinGecko aggregate).
2s.io
2s.io
Historical total-value-locked (TVL) time series for a DeFi protocol by slug (e.g. aave, lido, uniswap), via DefiLlama (free/keyless). Returns daily { date, tvlUsd } points (most recent N, default 90) plus the protocol's chains. For charting a protocol's growth or decline over time. Net-new vs crypto.defi (current TVL only).
2s.io
2s.io
Live native + ERC-20 token balances for an EVM address (Base, Ethereum, Polygon, Arbitrum, Optimism; keyless). Returns the native-coin balance and, for any ERC-20 contract addresses you pass, the symbol, decimals, raw and human-formatted balance — fetched in one multicall. For wallet dashboards, treasury checks, and agent payment/settlement flows.
2s.io
2s.io
Historical market chart for a coin by CoinGecko id: time-series of price, market cap, and volume over the last N days (1-365) in USD or another vs-currency. Granularity is auto-selected by range (hourly for short windows, daily for long). For backtests, charts, and trend analysis.
2s.io
2s.io
Centralized-exchange OHLCV candlesticks for a spot trading pair (e.g. BTC-USD, ETH-USD, SOL-USD), free/keyless. Pass interval (1m/5m/15m/1h/6h/1d) and limit. Each bar: time, open, high, low, close, volume. Net-new vs crypto.dex-ohlcv (on-chain DEX) — this is CEX spot.
2s.io
2s.io
Decode and validate a product barcode (GTIN / UPC-A / EAN-13 / EAN-8 / GTIN-14 / ISBN-13 / ISSN). Returns the GS1 mod-10 check-digit validation (valid flag + expected digit — an LLM can't reliably compute this), the symbology, the zero-padded GTIN-14 canonical form, and the GS1 prefix decoded to the issuing GS1 member organisation and its country (NOTE: that's the country of the org that issued the prefix, not necessarily where the item was made). Flags restricted-distribution (in-store/variable-measure) prefixes and Bookland (ISBN) / serial (ISSN) ranges. Also attempts a FRESH best-effort product-identity lookup (name, brand, category, image) across the open Open Food/Beauty/Products/Pet Food Facts federation (ODbL) — reliable for food, beverage, and beauty items, sparse for general retail (electronics/apparel), and may be null. Always live (no caching). Set identity=false to skip the lookup and decode only.
2s.io
2s.io
Full ClinicalTrials.gov study record by NCT id — the deep detail beyond clinical.trial-search's summary. Returns the brief + detailed description, status, phases, conditions, study design (allocation, intervention model, primary purpose, masking), enrollment, interventions, primary and secondary outcome measures (with time frames), full eligibility criteria (inclusion/exclusion text, sex, age range, healthy-volunteers, standard age groups), lead sponsor and collaborators, all facility locations (name, city, state, country), whether results are posted, and key dates. Free, public-domain (NIH NLM). Use clinical.trial-search to find an NCT id, then this for the complete protocol.
2s.io
2s.io
All DEX pools trading a given token, by contract address (via GeckoTerminal, free/keyless). Returns each pool's pair, on-chain USD price, FDV/market cap, liquidity reserve, 24h volume + price change, and buys/sells — the on-chain price + liquidity picture for any token across a network's DEXes.
2s.io
2s.io
DeFi TVL leaderboard across all chains (via DefiLlama, free/keyless): every chain ranked by total value locked, with its native token symbol and chain id. Distinct from crypto.defi (which returns one chain's TVL by name) — this is the full ranked cross-chain comparison.
2s.io
2s.io
Live on-chain token metadata for an ERC-20 or ERC-721 contract (Base, Ethereum, Polygon, Arbitrum, Optimism; keyless). Returns name, symbol, decimals, detected standard, and total supply (raw + formatted). The authoritative read straight from the contract — complements crypto.token-price and crypto.contract (ABI/source).
2s.io
2s.io
US federal campaign finance from the FEC (openFEC). Two modes: pass name to search candidates (returns FEC candidate id, party, office, state, district, incumbent/challenger, status, and election cycles); or pass candidateId (e.g. P80000722) to get that candidate's aggregate financial totals — total receipts, disbursements, cash on hand, and individual / PAC / party / self contributions in USD for the newest cycle, alongside identity. Free, public-domain (FEC). Search by name first, then pass a returned candidateId back in for the money. For donor/spend diligence, political research, and disclosure lookups.
2s.io
2s.io
Solar irradiance + PV-yield forecast for any coordinate (free/keyless, global). Returns a daily 1-16 day forecast: GHI (kWh/m²), peak sun hours, sunshine hours, and estimated yield per kWp of panels (at a 0.75 performance ratio). For rooftop-solar planning, agrivoltaics, and EV-charge scheduling. Complements energy.solar-resource (NREL long-run averages, US).
2s.io
2s.io
Unspent transaction outputs (UTXOs) for a Bitcoin address (free/keyless): each with txid, output index, value (sats + BTC), confirmation status, and block height. Sorted largest-first. For coin selection, balance verification, and wallet tooling.
2s.io
2s.io
On-chain token metrics by contract address (via GeckoTerminal, free/keyless): name, symbol, decimals, on-chain USD price, FDV, market cap, total reserve in USD, 24h volume, total + normalized supply, image, and CoinGecko id. Distinct from crypto.token-price (CoinGecko aggregate spot) — this is DEX-derived on-chain data for any token across 100+ networks.
2s.io
2s.io
Official US weather forecast for a coordinate (US land + territories). Pass lat + lon. Returns the National Weather Service forecast as a list of periods — by default ~7 days of day/night periods; pass hourly=true for an hour-by-hour forecast. Each period gives the temperature + unit, wind speed/direction, chance of precipitation, and a short + detailed forecast, plus the resolved city/state and issuing office. Source: US National Weather Service (api.weather.gov), public domain. For active warnings use weather.alerts.
2s.io
2s.io
Historical daily weather for any coordinate (ERA5 reanalysis, 1940→~5 days ago). Pass lat + lon + start + end (YYYY-MM-DD, range ≤366 days). Returns per-day max/min/mean temperature (°C), precipitation total (mm) + hours, and max wind (km/h). Source: Open-Meteo archive / ECMWF ERA5 (keyless).
2s.io
2s.io
Live ERC-721 NFT read (Base, Ethereum, Polygon, Arbitrum, Optimism; keyless). Given a contract + tokenId: returns current owner, collection name/symbol, and tokenURI (IPFS auto-resolved to a gateway URL). Pass metadata=1 to also fetch and normalize the token's JSON metadata (name, description, image, attributes). For NFT provenance, ownership checks, and gallery rendering.
2s.io
2s.io
Canadian-market vehicle dimensions and weights from NHTSA vPIC's Canadian Vehicle Specifications dataset. Pass year + make (required) and optional model to narrow. Returns one entry per matching trim with labeled dimensions — overall length/width/height (cm), wheelbase (cm), curb weight (kg), front/rear track width, interior head/leg/shoulder/hip room, and weight distribution — plus the full raw spec map. Authoritative measured specs (the SAE dimension codes), not estimates. Keyless, public-domain; covers model years 1971+.
2s.io
2s.io
Corporate ownership graph for a legal entity by LEI (GLEIF Level-2 relationships, live). Returns the direct parent and ultimate parent (each: LEI, legal name, jurisdiction, country, status), the direct children (paged), and total counts of direct and ultimate children. The authoritative 'who owns whom' lookup for KYB, beneficial-ownership, and corporate-tree mapping — complements business.lei (entity reference) and business.lei-isins.
2s.io
2s.io
DeFi yield & lending rates across protocols (via DefiLlama, free/keyless). Returns pools ranked by APY or TVL with base vs reward APY, TVL, 1d/7d/30d APY trend, stablecoin flag, and IL-risk. Filter by chain, project (aave, compound, lido…), symbol (USDC, ETH…), minApy, minTvlUsd. The yield/lending-rate layer beyond crypto.defi's TVL headline.
2s.io
2s.io
Bitcoin mempool state (free/keyless): current unconfirmed tx count, total vsize, and total fees, plus the most recent transactions (whale radar) — filter with minBtc to surface only large pending transfers. For congestion monitoring and large-transfer alerts.
2s.io
2s.io
Determine the FEMA flood zone for a coordinate. Pass lat and lon. Returns the FEMA flood zone code (e.g. AE, VE, X), its subtype, whether the point is in a Special Flood Hazard Area (isSFHA — the 1% annual-chance floodplain where flood insurance is mandatory for federally backed mortgages), a plain-language risk level (high / moderate / minimal / undetermined / unmapped) and description, the static base flood elevation and depth when published, and the source FIRM panel id. Data: FEMA National Flood Hazard Layer (NFHL), free and public-domain. When no flood polygon intersects the point, returns mapped=false (usually Zone X / minimal risk or unmapped — not a guarantee of zero risk). Use for property risk screening, insurance/mortgage context, and siting decisions; geocode an address with /api/geocode/address first to get the coordinate.