2s.io

https://2s.io/api/medical/drug-status

Shares a payout wallet with 441 other endpoints — its adoption is attributed from that shared wallet's traffic, not earned exclusively.

One-call drug situational awareness. Give a drug name (resolved to a canonical RxCUI via NIH RxNorm), or an exact rxcui or ndc you already hold, and get back: whether it is currently in FDA shortage, any open or recent FDA recalls, and FDA NDC-directory metadata (labeler, DEA schedule, pharmaceutical class, marketing status). Returns a resolved identity block plus hasCurrentShortage / hasOpenRecall booleans and one found/error block per source (shortages, ndc, recalls). Composition of NIH RxNorm + OpenFDA drug-shortages, NDC directory, and recall enforcement — all free, public-domain US government data; each source degrades independently. Point-in-time public records, not medical advice. Use for pharmacy/supply-chain triage, prescribing-support agents, and verifying a drug is real, scheduled, and available before acting.

67
reliability

Reliability & health

Uptime and response time from our own unpaid probes, plus the reliability score built from them.

7 days 30 days

Uptime

100.0% avg
0% 50% 100% Jul 22Aug 1Aug 10Aug 20

Response time

p50 59ms · p95 140ms
0ms 250ms 500ms Jul 22Aug 1Aug 10Aug 20
Data table
Reliability history per time bucket over the last 30 days (daily).
Bucket Uptime Probes Response time
7/22/2026, 12:00:00 AM 100% 1 57ms
7/23/2026, 12:00:00 AM 100% 1 57ms
7/24/2026, 12:00:00 AM 100% 1 488ms
7/25/2026, 12:00:00 AM 100% 1 288ms
7/26/2026, 12:00:00 AM 100% 1 142ms
7/27/2026, 12:00:00 AM 100% 1 83ms
7/28/2026, 12:00:00 AM 100% 1 182ms
7/29/2026, 12:00:00 AM 100% 1 54ms
7/30/2026, 12:00:00 AM 100% 1 63ms
7/31/2026, 12:00:00 AM 100% 1 50ms
8/1/2026, 12:00:00 AM 100% 1 54ms
8/2/2026, 12:00:00 AM 100% 1 68ms
8/3/2026, 12:00:00 AM 100% 1 212ms
8/4/2026, 12:00:00 AM 100% 1 56ms
8/5/2026, 12:00:00 AM 100% 1 79ms
8/6/2026, 12:00:00 AM 100% 1 65ms
8/7/2026, 12:00:00 AM 100% 1 66ms
8/8/2026, 12:00:00 AM 100% 1 47ms
8/9/2026, 12:00:00 AM 100% 1 55ms
8/10/2026, 12:00:00 AM 100% 1 57ms
8/11/2026, 12:00:00 AM 100% 1 47ms
8/12/2026, 12:00:00 AM 100% 1 60ms
8/13/2026, 12:00:00 AM 100% 1 62ms
8/14/2026, 12:00:00 AM 100% 1 55ms
8/15/2026, 12:00:00 AM 100% 1 62ms
8/16/2026, 12:00:00 AM 100% 1 54ms
8/17/2026, 12:00:00 AM 100% 1 65ms
8/18/2026, 12:00:00 AM 100% 1 213ms
8/19/2026, 12:00:00 AM 100% 21 61ms
8/20/2026, 12:00:00 AM 100% 18 57ms
67
Composite reliability — the weighted average of the dimensions below, on a 0–100 scale.
Availability
100

How often it was reachable when we probed it (weight 35%).

Latency
100

How quickly it answers when it is up — fast scores high (weight 20%).

Security
100

Whether it serves over working TLS / https (weight 15%).

Transparency
61

Whether the operator disclosed what it does — description, schema, identity (weight 15%).

Activity
14

Observed on-chain payments to this endpoint's wallet — transactions, volume, and distinct paying wallets over the last month (weight 15%; not yet measured when we have not seen its wallet settle).

Confidence 100% — how much probe evidence backs this score. A thin history is flagged, not hidden.

See the scoring methodology for exactly how each number is computed.

Payment

Currencies
USDC
Networks
base, solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp
Facilitator
unknown
SDK
unknown

Operator

Company
inferred — unknown
Jurisdiction
—
Registrar
—
Domain registered
—
Hosting network
VERCEL-09
Hosting country
—

Operator context is derived from public RDAP/TLS records and unverified. Company and country are only available for endpoints that publish them (an OV/EV TLS certificate or a non-redacted domain record); most endpoints are CDN-fronted and disclose neither.

On-chain activity (base)

13,870
payments (30d)
39.16
USD volume (30d)
186
paying wallets (30d)

Payments per day

last payment 8/20/2026
0 1000 2000 Jul 22Aug 1Aug 10Aug 20
Data table
Settled payments per day.
Day Payments Volume (USD) Paying wallets
7/22/2026 984 2.17 102
7/23/2026 629 1.66 89
7/24/2026 1,232 2.49 117
7/25/2026 1,341 2.61 128
7/26/2026 915 1.98 107
7/27/2026 1,175 2.1 107
7/28/2026 762 1.71 86
7/29/2026 852 1.67 97
7/30/2026 818 1.74 97
7/31/2026 882 1.7 94
8/1/2026 633 1.24 82
8/2/2026 604 1.12 76
8/3/2026 358 1.6 47
8/4/2026 530 3.35 70
8/5/2026 408 2.76 42
8/6/2026 272 2.14 32
8/7/2026 164 1.37 23
8/8/2026 127 1.51 17
8/9/2026 60 0.33 10
8/10/2026 109 0.36 8
8/11/2026 84 0.25 8
8/12/2026 84 0.25 6
8/13/2026 73 0.21 6
8/14/2026 167 1.05 6
8/15/2026 24 0.1 4
8/16/2026 338 0.86 2
8/17/2026 63 0.18 3
8/18/2026 55 0.16 2
8/19/2026 84 0.23 3
8/20/2026 43 0.25 6

This payout wallet is shared: figures cover all 442 endpoints paid at it, since payments cannot be attributed to one of them. Only payments settled on chains and facilitators we index.

Linked by wallet — likely same operator

On-chain agent identity and the x402 endpoint that shares its settlement wallet.

https://2s.io/api/crypto/ens-resolve x402 endpoint https://2s-3cpr6qm6j-alleyford.vercel.app/api/convert/unit x402 endpoint
Response schema 
{
  "properties": {
    "data": {
      "additionalProperties": false,
      "properties": {
        "hasCurrentShortage": {
          "nullable": true,
          "type": "boolean"
        },
        "hasOpenRecall": {
          "nullable": true,
          "type": "boolean"
        },
        "ndc": {
          "additionalProperties": false,
          "properties": {
            "data": {
              "additionalProperties": {},
              "nullable": true,
              "type": "object"
            },
            "error": {
              "nullable": true,
              "type": "string"
            },
            "found": {
              "type": "boolean"
            }
          },
          "required": [
            "found",
            "error",
            "data"
          ],
          "type": "object"
        },
        "note": {
          "type": "string"
        },
        "query": {
          "additionalProperties": false,
          "properties": {
            "drug": {
              "nullable": true,
              "type": "string"
            },
            "ndc": {
              "nullable": true,
              "type": "string"
            },
            "rxcui": {
              "nullable": true,
              "type": "string"
            }
          },
          "required": [
            "drug",
            "rxcui",
            "ndc"
          ],
          "type": "object"
        },
        "recalls": {
          "additionalProperties": false,
          "properties": {
            "data": {
              "additionalProperties": {},
              "nullable": true,
              "type": "object"
            },
            "error": {
              "nullable": true,
              "type": "string"
            },
            "found": {
              "type": "boolean"
            }
          },
          "required": [
            "found",
            "error",
            "data"
          ],
          "type": "object"
        },
        "resolved": {
          "additionalProperties": false,
          "properties": {
            "matchScore": {
              "nullable": true,
              "type": "number"
            },
            "name": {
              "nullable": true,
              "type": "string"
            },
            "rxcui": {
              "nullable": true,
              "type": "string"
            },
            "termType": {
              "nullable": true,
              "type": "string"
            }
          },
          "required": [
            "rxcui",
            "name",
            "termType",
            "matchScore"
          ],
          "type": "object"
        },
        "shortages": {
          "additionalProperties": false,
          "properties": {
            "data": {
              "additionalProperties": {},
              "nullable": true,
              "type": "object"
            },
            "error": {
              "nullable": true,
              "type": "string"
            },
            "found": {
              "type": "boolean"
            }
          },
          "required": [
            "found",
            "error",
            "data"
          ],
          "type": "object"
        },
        "sources": {
          "items": {
            "$ref": "#/components/schemas/Source"
          },
          "type": "array"
        }
      },
      "required": [
        "query",
        "resolved",
        "hasCurrentShortage",
        "hasOpenRecall",
        "shortages",
        "ndc",
        "recalls",
        "sources",
        "note"
      ],
      "type": "object"
    },
    "meta": {
      "$ref": "#/components/schemas/CallMeta"
    }
  },
  "required": [
    "data",
    "meta"
  ],
  "type": "object"
}