api.biotechcatalystsentinel.com

https://api.biotechcatalystsentinel.com/v1/catalysts/upcoming

Shares a payout wallet with 2 other endpoints — its adoption is attributed from that shared wallet's traffic, not earned exclusively.

Upcoming FDA drug-approval (PDUFA) decision dates for US-listed biotechs — a forward catalyst calendar extracted from primary SEC 8-K/6-K filings, every date grounded in a verbatim filing quote and cited to its EDGAR accession. The difference from other catalyst feeds: each date is scored against the actual FDA decision, so accuracy is a public, auditable track record (median 1-day error) — verify it free at GET /v1/accuracy before you pay.

63
reliability

Reliability & health

Uptime and response time from our own unpaid probes, plus the reliability score built from them.

7 days 30 days

Uptime

100.0% avg
0% 50% 100% Fri 11 PMMon 6 AMWed 1 PMFri 8 PM

Response time

p50 385ms · p95 414ms
0ms 250ms 500ms Fri 11 PMMon 6 AMWed 1 PMFri 8 PM
Data table
Reliability history per time bucket over the last 7 days (hourly).
Bucket Uptime Probes Response time
8/14/2026, 11:00:00 PM 100% 1 380ms
8/15/2026, 12:00:00 AM 100% 1 383ms
8/15/2026, 1:00:00 AM 100% 1 373ms
8/15/2026, 2:00:00 AM 100% 1 397ms
8/15/2026, 3:00:00 AM 100% 1 399ms
8/15/2026, 4:00:00 AM 100% 1 390ms
8/15/2026, 6:00:00 AM 100% 1 411ms
8/15/2026, 7:00:00 AM 100% 1 388ms
8/15/2026, 8:00:00 AM 100% 1 386ms
8/15/2026, 9:00:00 AM 100% 1 379ms
8/15/2026, 10:00:00 AM 100% 1 389ms
8/15/2026, 11:00:00 AM 100% 1 401ms
8/15/2026, 12:00:00 PM 100% 1 394ms
8/15/2026, 1:00:00 PM 100% 1 379ms
8/15/2026, 3:00:00 PM 100% 1 378ms
8/15/2026, 4:00:00 PM 100% 1 379ms
8/15/2026, 5:00:00 PM 100% 1 386ms
8/15/2026, 6:00:00 PM 100% 1 404ms
8/15/2026, 7:00:00 PM 100% 1 370ms
8/15/2026, 8:00:00 PM 100% 1 387ms
8/15/2026, 10:00:00 PM 100% 1 377ms
8/15/2026, 11:00:00 PM 100% 1 403ms
8/16/2026, 12:00:00 AM 100% 1 405ms
8/16/2026, 1:00:00 AM 100% 1 400ms
8/16/2026, 2:00:00 AM 100% 1 387ms
8/16/2026, 3:00:00 AM 100% 1 385ms
8/16/2026, 5:00:00 AM 100% 1 385ms
8/16/2026, 6:00:00 AM 100% 1 411ms
8/16/2026, 7:00:00 AM 100% 1 369ms
8/16/2026, 8:00:00 AM 100% 1 376ms
8/16/2026, 9:00:00 AM 100% 1 397ms
8/16/2026, 10:00:00 AM 100% 1 402ms
8/16/2026, 12:00:00 PM 100% 1 377ms
8/16/2026, 1:00:00 PM 100% 1 406ms
8/16/2026, 2:00:00 PM 100% 1 399ms
8/16/2026, 3:00:00 PM 100% 1 372ms
8/16/2026, 4:00:00 PM 100% 1 373ms
8/16/2026, 5:00:00 PM 100% 1 405ms
8/16/2026, 7:00:00 PM 100% 1 385ms
8/16/2026, 8:00:00 PM 100% 1 367ms
8/16/2026, 9:00:00 PM 100% 1 373ms
8/16/2026, 10:00:00 PM 100% 1 380ms
8/16/2026, 11:00:00 PM 100% 1 398ms
8/17/2026, 12:00:00 AM 100% 1 378ms
8/17/2026, 2:00:00 AM 100% 1 403ms
8/17/2026, 3:00:00 AM 100% 1 374ms
8/17/2026, 4:00:00 AM 100% 1 392ms
8/17/2026, 5:00:00 AM 100% 1 381ms
8/17/2026, 6:00:00 AM 100% 1 419ms
8/17/2026, 7:00:00 AM 100% 1 397ms
8/17/2026, 9:00:00 AM 100% 1 398ms
8/17/2026, 10:00:00 AM 100% 1 382ms
8/17/2026, 11:00:00 AM 100% 1 378ms
8/17/2026, 12:00:00 PM 100% 1 383ms
8/17/2026, 1:00:00 PM 100% 1 379ms
8/17/2026, 2:00:00 PM 100% 1 376ms
8/17/2026, 4:00:00 PM 100% 1 377ms
8/17/2026, 5:00:00 PM 100% 1 382ms
8/17/2026, 6:00:00 PM 100% 1 380ms
8/17/2026, 7:00:00 PM 100% 1 381ms
8/17/2026, 8:00:00 PM 100% 1 360ms
8/17/2026, 9:00:00 PM 100% 1 384ms
8/17/2026, 11:00:00 PM 100% 1 373ms
8/18/2026, 12:00:00 AM 100% 1 381ms
8/18/2026, 1:00:00 AM 100% 1 381ms
8/18/2026, 2:00:00 AM 100% 1 385ms
8/18/2026, 3:00:00 AM 100% 1 385ms
8/18/2026, 4:00:00 AM 100% 1 381ms
8/18/2026, 6:00:00 AM 100% 1 396ms
8/18/2026, 7:00:00 AM 100% 1 400ms
8/18/2026, 8:00:00 AM 100% 1 376ms
8/18/2026, 9:00:00 AM 100% 1 392ms
8/18/2026, 10:00:00 AM 100% 1 392ms
8/18/2026, 11:00:00 AM 100% 1 380ms
8/18/2026, 1:00:00 PM 100% 1 387ms
8/18/2026, 2:00:00 PM 100% 1 414ms
8/18/2026, 3:00:00 PM 100% 1 404ms
8/18/2026, 4:00:00 PM 100% 1 381ms
8/18/2026, 5:00:00 PM 100% 1 374ms
8/18/2026, 6:00:00 PM 100% 1 397ms
8/18/2026, 8:00:00 PM 100% 1 389ms
8/18/2026, 9:00:00 PM 100% 1 374ms
8/18/2026, 10:00:00 PM 100% 1 388ms
8/18/2026, 11:00:00 PM 100% 1 440ms
8/19/2026, 12:00:00 AM 100% 1 370ms
8/19/2026, 1:00:00 AM 100% 1 403ms
8/19/2026, 3:00:00 AM 100% 1 374ms
8/19/2026, 4:00:00 AM 100% 1 380ms
8/19/2026, 5:00:00 AM 100% 1 361ms
8/19/2026, 6:00:00 AM 100% 1 396ms
8/19/2026, 7:00:00 AM 100% 1 367ms
8/19/2026, 8:00:00 AM 100% 1 391ms
8/19/2026, 10:00:00 AM 100% 1 357ms
8/19/2026, 11:00:00 AM 100% 1 377ms
8/19/2026, 12:00:00 PM 100% 1 368ms
8/19/2026, 1:00:00 PM 100% 1 383ms
8/19/2026, 2:00:00 PM 100% 1 369ms
8/19/2026, 3:00:00 PM 100% 1 403ms
8/19/2026, 4:00:00 PM 100% 1 399ms
8/19/2026, 6:00:00 PM 100% 1 375ms
8/19/2026, 7:00:00 PM 100% 1 385ms
8/19/2026, 8:00:00 PM 100% 1 381ms
8/19/2026, 9:00:00 PM 100% 1 372ms
8/19/2026, 10:00:00 PM 100% 1 395ms
8/19/2026, 11:00:00 PM 100% 1 391ms
8/20/2026, 1:00:00 AM 100% 1 389ms
8/20/2026, 2:00:00 AM 100% 1 430ms
8/20/2026, 3:00:00 AM 100% 1 381ms
8/20/2026, 4:00:00 AM 100% 1 379ms
8/20/2026, 5:00:00 AM 100% 1 382ms
8/20/2026, 6:00:00 AM 100% 1 447ms
8/20/2026, 7:00:00 AM 100% 1 380ms
8/20/2026, 8:00:00 AM 100% 1 386ms
8/20/2026, 10:00:00 AM 100% 1 388ms
8/20/2026, 11:00:00 AM 100% 1 383ms
8/20/2026, 12:00:00 PM 100% 1 401ms
8/20/2026, 1:00:00 PM 100% 1 384ms
8/20/2026, 2:00:00 PM 100% 1 376ms
8/20/2026, 3:00:00 PM 100% 1 371ms
8/20/2026, 4:00:00 PM 100% 1 377ms
8/20/2026, 6:00:00 PM 100% 1 406ms
8/20/2026, 7:00:00 PM 100% 1 392ms
8/20/2026, 8:00:00 PM 100% 1 379ms
8/20/2026, 9:00:00 PM 100% 1 426ms
8/20/2026, 10:00:00 PM 100% 1 414ms
8/20/2026, 11:00:00 PM 100% 1 390ms
8/21/2026, 1:00:00 AM 100% 1 369ms
8/21/2026, 2:00:00 AM 100% 1 425ms
8/21/2026, 3:00:00 AM 100% 1 396ms
8/21/2026, 4:00:00 AM 100% 1 387ms
8/21/2026, 5:00:00 AM 100% 1 413ms
8/21/2026, 6:00:00 AM 100% 1 383ms
8/21/2026, 7:00:00 AM 100% 1 379ms
8/21/2026, 9:00:00 AM 100% 1 386ms
8/21/2026, 10:00:00 AM 100% 1 411ms
8/21/2026, 11:00:00 AM 100% 1 367ms
8/21/2026, 12:00:00 PM 100% 1 376ms
8/21/2026, 1:00:00 PM 100% 1 403ms
8/21/2026, 2:00:00 PM 100% 1 392ms
8/21/2026, 3:00:00 PM 100% 1 380ms
8/21/2026, 5:00:00 PM 100% 1 387ms
8/21/2026, 6:00:00 PM 100% 1 378ms
8/21/2026, 7:00:00 PM 100% 1 382ms
8/21/2026, 8:00:00 PM 100% 1 415ms
63
Composite reliability — the weighted average of the dimensions below, on a 0–100 scale.
Availability
100

How often it was reachable when we probed it (weight 35%).

Latency
97

How quickly it answers when it is up — fast scores high (weight 20%).

Security
100

Whether it serves over working TLS / https (weight 15%).

Transparency
67

Whether the operator disclosed what it does — description, schema, identity (weight 15%).

Activity
10

Observed on-chain payments to this endpoint's wallet — transactions, volume, and distinct paying wallets over the last month (weight 15%; not yet measured when we have not seen its wallet settle).

Confidence 100% — how much probe evidence backs this score. A thin history is flagged, not hidden.

See the scoring methodology for exactly how each number is computed.

Payment

Currencies
USDC
Networks
base, solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp
Facilitator
unknown
SDK
unknown

Operator

Company
inferred — unknown
Jurisdiction
—
Registrar
Cloudflare, Inc.
Domain registered
2026-06-23
Hosting network
CLOUD-NBG1
Hosting country
DE

Operator context is derived from public RDAP/TLS records and unverified. Company and country are only available for endpoints that publish them (an OV/EV TLS certificate or a non-redacted domain record); most endpoints are CDN-fronted and disclose neither.

On-chain activity (base)

10
payments (30d)
0.23
USD volume (30d)
8
paying wallets (30d)

Payments per day

last payment 8/20/2026
0 3 5 Jul 26Aug 7Aug 16Aug 20
Data table
Settled payments per day.
Day Payments Volume (USD) Paying wallets
7/26/2026 1 0.02 1
7/28/2026 1 0.02 1
8/7/2026 1 0.02 1
8/12/2026 1 0.02 1
8/14/2026 3 0.09 2
8/16/2026 1 0.02 1
8/18/2026 1 0.02 1
8/20/2026 1 0.02 1

This payout wallet is shared: figures cover all 3 endpoints paid at it, since payments cannot be attributed to one of them. Only payments settled on chains and facilitators we index.

Linked by wallet — likely same operator

On-chain agent identity and the x402 endpoint that shares its settlement wallet.

https://api.biotechcatalystsentinel.com/v1/events x402 endpoint
Response schema 
{
  "$ref": "#/components/schemas/ApiResponse_list_CatalystOut__"
}